This perspective identifies the grand challenges in arachnid science:
1. Grasp the arachnid species diversity.
2. Standardize arachnid systematics research.
3. Interpret arachnid trait evolution through omics approaches.
4. Facilitate biotechnological applications of arachnid molecules and biomaterials.
5. Utilize arachnids as models in ecological and biogeographic research.
6. Disentangle evolutionary drivers of arachnid diversity.
7. Define effective conservation measures for arachnids in the light of global changes.
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